There are three types of calcium antagonists commonly used clinically to prevent and treat coronary artery disease: 1. Dihydropyridines: such as nifedipine, nicardipine, amlodipine, etc. The effect of lowering blood pressure is more obvious and can reduce the anterior and posterior loads, but has the effect of increasing the heart rate. It is mainly used to lower blood pressure. Ren Yusheng, Department of Cardiovascular Medicine, Shanghai Changzheng Hospital 2, benzodiazepines: such as diltiazem, has a lower heart rate, negative inotropic effect, can significantly dilate the coronary arteries, can be used to treat coronary artery spasm. 3, benzodiazepines: such as isoptin, with lower heart rate, negative inotropic force and inhibition of conduction, with anti-arrhythmic effect. Patients should choose different types of calcium antagonists according to their conditions and under the guidance of physicians.