Collagen filler can improve wrinkles, but it needs to be filled repeatedly; if accompanied by obvious skin laxity, it needs to be combined with photoelectric and surgical treatments. Collagen filling can support the structural contour, effectively maintain skin tension and keep skin elasticity, so that the wrinkles will fade or disappear. However, the implanted collagen will slowly lose its shape, and eventually be decomposed and absorbed by the body, and the wrinkles will reappear when the filled collagen material disappears, therefore, collagen filling cannot get rid of wrinkles. Daily life management of wrinkles, focusing on the development of a good dietary habits, daily can eat more collagen-rich foods, drink more water, go out and do a good job of sunscreen, maintain adequate sleep and a good mood, can delay the production of wrinkles. On the other hand, there are fewer CFDA-certified collagen fillers, and those who are willing to be treated are recommended to go to regular medical institutions to avoid adverse consequences.