Low progesterone shot progesterone can be discontinued, but not immediately. Under normal circumstances, progesterone returns to normal at about 12 weeks of gestation, because at about 12 weeks of gestation, the placenta has formed, at which time the ovarian luteal function subsides and the placenta will replace the luteal function in the body to secrete progesterone. Progesterone can be stopped only after the pregnant woman has been checked in the hospital to make sure that the level of progesterone secretion in her body is normal, that is, the progesterone has returned to normal level and there is no vaginal bleeding, abdominal pain and other phenomena of preterm abortion. However, it should be noted that when stopping the medication, it should not be stopped immediately, otherwise it may lead to a sudden drop in progesterone, thus increasing the risk of miscarriage. Therefore, when stopping the medication, you need to gradually reduce the dosage, and then switch to oral progesterone capsules, and recheck the progesterone value after 1 week, if the result is normal, then you can stop the medication. Pregnant women should review their progesterone values regularly when they are on birth control because progesterone within the normal range during pregnancy reduces uterine excitability, inhibits uterine activity and relaxes smooth muscle, providing support and security for early fetal growth and development. If progesterone is low, maternal immune rejection of the fetus may occur, increasing the risk of miscarriage and even requiring fertility preservation treatment under medical supervision.