Most moles on the face or other parts of the body are benign and can “live peacefully” with their owners without any treatment. However, some moles need to be treated. 1.Moles that are too big The size of a mole can sometimes indicate whether it will cause trouble in the future. Studies have shown that larger moles have a higher chance of malignancy than smaller ones (except for giant moles). 2. Moles that are easily rubbed Moles that grow in areas that are easily rubbed have a higher chance of becoming malignant. For example, pigmented moles on the palms and feet, neck, armpits, chest, head, back, genitalia and other parts prone to wear and tear have a high chance of malignant transformation and must be regularly observed or directly removed to prevent malignant transformation and transfer. 3. Exposed moles Sunlight or ultraviolet rays may increase the chances of moles changing, so moles on long-term exposed parts are best to be removed. Moles on the extremities Moles on the soles of the feet are the most common sites for melanoma, and according to medical statistics, moles on the ends of the extremities, such as those under the fingers or nails, should be given special attention. Most of the malignant melanomas in the East occur on the hands and feet. Therefore, if you find that moles on the palms of your hands and feet are growing abnormally fast, you should seek medical attention as soon as possible.