In general, the conversion of minor triple positive to minor double positive indicates that the condition has improved, but it is not absolute and does not require special treatment. Hepatitis B minor triple positive refers to positive hepatitis B surface antigen, hepatitis B e antibody and hepatitis B core antibody. Hepatitis B minor bi-yang is positive for hepatitis B surface antigen and hepatitis B core antibody, and hepatitis B e antibody is negative. There is basically no essential difference between minor tri-positive and minor bi-positive, and a change in the test indicates an improvement in the condition. Whether the condition has improved or not should be judged by combining the quantitative hepatitis B virus DNA, liver function and liver ultrasound test results of the infected person. If the condition is not stabilized, there is a possibility that it will turn into minor triple positive or even major triple positive. If treatment is needed, it is recommended to actively cooperate with the doctor to carry out liver-protecting and anti-viral treatments, and the commonly used drugs include entecavir and tenofovir. In addition to the above, hepatitis B small triple positive to small second positive also has the possibility of virus mutation in the body, it is recommended to find out the cause of the disease in a timely manner, and take treatment as soon as possible if necessary.