Lid xanthomas occur in the upper and lower eyelids and are yellow or orange patches of skin caused by lipid deposits in the eyelids. The main treatments for lid xanthoma are medication, physical therapy, and surgery.1. Medication: Because of individual differences, the best, fastest, and most effective medication does not exist, and patients should use it regularly according to medical advice. Pingyangmycin can shrink the tumor, but may be accompanied by fever, gastrointestinal and skin adverse reactions. Fluorouracil can promote tumor shedding and may be accompanied by gastrointestinal reactions, such as nausea, vomiting and diarrhea, etc. In serious cases, the drug should be discontinued immediately and medical attention should be sought promptly. Heparin sodium is indicated for patients without active bleeding or no bleeding tendency. Trichloroacetic acid can make the tumor necrotic and fall off, but it is easy to cause burns on the skin, so large area should be avoided. 2. Physical therapy: such as cryotherapy, liquid nitrogen is commonly used to make the tumor locally frozen necrotic and fall off, which is less traumatic but easy to recur. Microwave therapy uses thermal effect to cause local necrosis and shedding of the tumor, which is less traumatic but cannot treat deep lid xanthoma, and too many times of freezing will cause damage to the skin. Electrocautery treatment burns the tumor through the very high heat of electric sparks, causing rapid vaporization and rapid relief of symptoms after treatment. Laser treatment is a newer treatment method that can precisely locate the tumor, is less traumatic, and has good results, and is currently used more often. 3. Surgery: This is suitable for patients whose medication is ineffective and whose tumor is large, and if the patient’s skin lesions are too large, a skin graft can be performed after surgery. In addition, if patients have hyperlipidemia, they should have a low-fat, low-cholesterol and low-sugar diet, especially they should strictly control the intake of fatty meat, lard, animal offal and other high-cholesterol foods, and they should eat more fresh vegetables and fruits, which will help the lid xanthoma to subside.