The common symptoms of intracranial fungal infections mainly cause patients to develop central hyperthermia, elevated body temperature, headache, and some patients may also have these symptoms of confusion and irritability, and some patients may also have focal seizures. When the symptoms of intracranial infection are severe, the patient may also experience convulsions of the limbs and loss of consciousness, and often the patient may also have increased intracranial pressure, severe headache, nausea, vomiting, and other problems. Intracranial fungal infections are mainly seen in patients with low resistance, and treatment of intracranial infections is relatively difficult. Because of the difficulty in diagnosing intracranial infections, repeated lumbar punctures of the cerebrospinal fluid are required for fungal cultures. However, even in a tertiary care hospital, the positive culture rate may only be about 10%, and there is a blood-brain barrier in the brain, so many antifungal drugs have a high concentration in the blood, but not in the cerebrospinal fluid, making treatment difficult.