Condoms are a commonly used male contraceptive that has many wonderful effects and uses besides contraception, the ability to cure infertility being one of them. Of course, by infertility here, we do not mean that any infertility can be cured, but rather a specific kind of infertility. In recent years, studies have found that some healthy couples with no obvious cause for infertility are suffering from an anti-sperm antibody, suggesting that infertility has some relationship with immunity, which is medically known as “immune infertility”. Immunological infertility is caused by autoimmunity in men, which generates antibodies against their own sperm, causing sperm agglutination, inactivity or death, resulting in the formation of dead sperm or weak sperm, causing infertility. In women, as the husband’s semen and sperm become an antigen in the vagina and are absorbed by the vaginal or cervical epithelium, an antibody against the husband’s sperm is produced in the blood or in the cervical mucus, which can make the sperm that has penetrated the cervix inactive, agglutinated or dead, thus preventing conception. Individual women even have acute allergic reactions to their husbands’ semen, i.e. hives, asthma, uterine pain, etc. after sex, and even deficiency. Immunological infertility can be treated by sperm flushing fertilization method and immunosuppression method of methylprednisolone in men. When the woman has anti-sperm antibodies, the man should insist on using condoms uninterruptedly for three months to six months during sex so that semen does not enter the vagina. In this way, the woman’s anti-sperm antibody potency decreases significantly, and the chance of conception can reach about 34% once she lives without a condom type. For those infertile couples who are in good health and have no obvious reasons for the test, it is recommended that you adopt this method, and you may get unexpected results in conception.