Down’s syndrome screening and obstetrics 4D ultrasound during pregnancy I. Down’s syndrome screening Common screening methods: 1. Determination of fetal-related markers in the mother’s blood, combined with maternal age, weight, height, gestational weeks, history of diabetes and other information to assess the risk rate of fetal disease. (Screening time: 14-20 weeks of pregnancy) Wang Qi, Department of Obstetrics and Gynecology, Second Hospital of Chifeng City 2. Ultrasound: Measurement of fetal nuchal translucency thickness (NT) at 11-13 weeks of pregnancy, NT value is more than normal, the risk rate increases. Second, fetal malformation screening Fetal neural tube malformation (including anencephaly, crural bifida), congenital heart disease, abdominal bifida, cleft lip and other fetal malformations, can be screened during pregnancy by four-dimensional ultrasound. (Screening time: 20-26 weeks of pregnancy) C. Obstetrics 4D also known as four-dimensional ultrasound 1, determine the age of the fetus; 2, analyze the development of the fetus; 3, evaluation of multiple births or / and high-risk pregnancies; 4, detection of fetal anomalies; 5, detection of structural abnormalities of the uterus; 6, detection of abnormalities of the placenta and so on. ToRCH antibody test for infections during pregnancy Toxoplasma gondii; other coxsackieviruses, chlamydia, etc.; rubella virus; cytomegalovirus; herpes simplex virus, combining the first letter of the English language, abbreviated as TORCH. In view of the fact that some viruses can cause harm to women and babies, eugenic experts advocate Jmm to do a viral antibody test before or during pregnancy, which is called eugenic five, also known as TORCH.