Moles are generally referred to as pigmented nevi. The efficacy of liquid nitrogen cryotherapy varies depending on the specifics of the pigmented nevus, including the size, location and depth of the nevus. Liquid nitrogen cryotherapy mainly uses the low temperature of liquid nitrogen to act on the tissue, causing it to become necrotic, and then acts as a treatment. If the lesion is deep, it may not be completely removed. In general, freezing is more effective for shallow and small pigmented nevi. It is worth noting that nevus has the possibility of malignant transformation, so patients with nevus need to go to the hospital for diagnosis and choose the appropriate treatment plan under the guidance of the doctor.