It is normal for patients with adenomyosis to not have a period after receiving two doses of leuprolide or goserelin acetate. Leuprolide or Goserelin Acetate are gonadotropin-releasing hormone agonists, which are often used to treat adenomyosis and endometriosis, and can provide effective and rapid relief of dysmenorrhea, treat excessive menstruation and reduce the size of the uterus. Some patients experience menopause while on the drug, and menstruation gradually recovers after discontinuing the drug. A very small number of women enter menopause during treatment and menstruation does not return after discontinuing treatment. Its common adverse reactions include decreased libido, flushing, excessive sweating, acne, vulvovaginal dryness, breast enlargement, and mild bruising at the injection site. If the above adverse reactions occur, it is recommended to consult the hospital in time, and the symptomatic treatment and adjustment of medication can be carried out under the guidance of physicians.