There are many reasons for high creatinine, if it is caused by gastrointestinal bleeding, drug damage, etc., generally need to correct the cause, if necessary, can use drugs such as prednisone acetate; if it is caused by glomerulonephritis, etc., generally need to comply with the doctor’s advice to choose prednisone acetate, renal failure and so on. In addition, physiological factors, such as strenuous exercise, etc., do not need to use drugs, pay attention to rest, regular review can be. Increased creatinine indicates that renal function is damaged, common acute causes include gastrointestinal bleeding, drug damage, heart failure, urinary tract obstruction, etc. Different treatment programs are adopted for different causes, such as transfusion of red blood cells to correct anemia, discontinue the damaged drugs, improve cardiac function, relieve obstruction, and use prednisone acetate and cyclophosphamide as prescribed by the doctor if necessary. Other chronic causes of increased creatinine, such as glomerulonephritis, diabetic nephropathy, etc., you can take oral prednisone acetate, cyclophosphamide, dagliflozin and other drugs under the guidance of a physician, and you can also choose some proprietary Chinese medicines, such as urethane particles, renal failure capsule, Haikun renal capsule, medicinal charcoal tablets, etc., to assist in lowering creatinine. In addition, physiological factors, such as strenuous exercise, eating a lot of meat, etc., do not need to use drugs, pay attention to rest, light diet, regular review can be. If the effect of drug treatment is poor and the blood creatinine rises progressively, renal replacement therapy is feasible if necessary. In addition to medication, in terms of diet, low-salt, low-fat, high-quality protein, reduce the burden on the kidneys, and remember not to blindly use drugs. It is recommended to go to regular hospitals for consultation and standardized treatment under the guidance of doctors.