The cause of kidney stones is not clear, can be combined with the patient’s condition to apply painkillers, antispasmodic drugs, stone dissolving drugs, stone removing drugs and other drugs for treatment. 1. Painkillers: for the symptoms of pain, indomethacin, tramadol and other drugs can be applied under the guidance of the doctor for treatment. 2. Antispasmodics: for the symptoms of muscle spasm, atropine sulfate, scopolamine and other drugs can be applied as prescribed by the doctor for treatment. 3. Stone dissolving drugs: common stones include uric acid stones and cystine stones, which should be treated with different drugs. (1) Uric acid stone: patients can apply sodium bicarbonate alkali, sodium hydrogen potassium citrate and other drugs for treatment under the guidance of doctors. (2) cystine stones: can be under the guidance of the doctor to apply acetylcysteine and other drugs for treatment. 4. Exclusion drugs: for small stones, you can follow the doctor’s instructions to apply tamsulosin and other drugs for treatment. To summarize, patients with kidney stones have different conditions, corresponding treatment measures, must follow the doctor’s instructions. After the use of drugs, patients may have rashes, nausea, vomiting, abdominal pain and other adverse reactions, should be as early as possible to seek medical treatment.