Neutrophils are an important component of the body’s intrinsic immune system and are among the cells that perform immune defense functions in areas of inflammation. In the case of simple low absolute neutrophil values, without other symptoms and blood abnormalities, there is usually no clinical significance. A decrease in absolute neutrophil count is common in the following cases: 1. Infection: Infection-induced low absolute neutrophil count is usually accompanied by fever and abnormalities at the site of infection, such as cough and diarrhea. It is common for viral infections to cause low absolute neutrophil values, such as influenza, measles, rubella, etc., usually accompanied by an increase in lymphocytes; some bacterial infections, such as typhoid fever, cornual tuberculosis patients, can also sometimes manifest as low absolute neutrophil values. The absolute neutrophil count is reduced. For infectious factors, it is usually necessary to improve the bacterial culture and apply anti-infective treatment with drugs such as antibiotics quinolones, macrolides, and aminoglycoside antibiotics. 2. Physical and chemical factors: radiotherapy, chemotherapy, and long-term exposure to X-rays can lead to absolute neutrophil reduction. Some anti-tuberculosis drugs, antibacterial drugs, interferon, and anti-thyroid drugs can also show a decrease in absolute neutrophil values, and patients usually have a history of related medications and treatments. It is necessary to combine with the doctor’s advice to change the treatment, treatment drugs, to alleviate the situation of neutrophil absolute value reduction; 3, blood system diseases: phagocytic syndrome, aplastic anemia, etc. can be manifested as neutrophil absolute value reduction, usually accompanied by other cell morphology and number of abnormalities such as red blood cell number reduction, as well as some systemic symptoms such as bleeding, pale lips, weakness. For example, doxorubicin, etoposide and methylprednisolone can be used to control the development of the disease, while cyclosporine can be used for immunosuppressive treatment in aplastic anemia and androgens can be used for hematopoietic treatment; 4. The absolute value of neutrophils is reduced due to the destruction of neutrophils by antibodies. Antiviral drugs, such as entecavir and tenofovir, can be applied for antiviral treatment, and surgery can be performed if necessary. Neutrophils play an extremely important role in the immune process against bacterial infections, and if neutrophils are too low, it may lead to infections and other diseases. It is recommended to seek medical treatment for low absolute neutrophil values, and you can take some leukostimulants such as ricoderm or inject recombinant human granulocyte colony-stimulating factor to promote absolute neutrophil values.