What is considered premature ejaculation (PE)? I have already explained this to you before, but I will add it again today. It is not possible to give a simple answer to this question. However, in general, in most cases, ejaculation occurs at the prelude to intercourse (i.e., when the hands, lips, or lower body begin to touch each other), which is a more severe form of premature ejaculation. If ejaculation occurs just after entering the vagina or within a few seconds of entering the vagina, it is also a more serious form of premature ejaculation. Most of the time, ejaculation occurs within two minutes of sexual intercourse, which is basically premature ejaculation. However, some experts believe that a man with normal neurological function is able to control enough time to satisfy a woman at will; a man who cannot make a woman with normal sexual function have at least a 50 percent chance of being satisfied (having an orgasm) is considered premature ejaculation. Premature ejaculation as a common male sexual dysfunction disease. It has become one of the most common diseases in the clinical treatment of urology and male medicine. With the continuous improvement of our socio-economic level and the change of people’s understanding of sex, the quality of sexual life is getting more and more attention and importance. Premature ejaculation plagues many male patients, and there are various different perceptions and treatments for premature ejaculation among the people. Many patients also have some questions about whether premature ejaculation can be cured or not. What exactly are the treatments for premature ejaculation? I will explain in detail below. (a) Psychological/behavioral treatment The goal of psychological/behavioral interventions is to help patients and sexual partners improve ejaculatory control by: ① learning to control and/or delay ejaculation; ② increasing confidence in sexual life; ③ reducing anxiety about sexual life; ④ changing stereotypical sexual life procedures; ⑤ eliminating barriers related to intimacy; ⑥ solving interpersonal problems that maintain premature ejaculation; ⑦ adapting to the presence of disturbing factors in the environment (vii) Adapt to the experience and idea of sexual life in the environment with disturbing factors; (viii) Improve the communication and exchange with sexual partners. (Oral western drug therapy: selective 5-hydroxytryptamine reuptake inhibitors (SSRIs), non-selective 5-hydroxytryptamine reuptake inhibitors. Topical treatment: ointments, gels or sprays of surface local anesthetics such as lidocaine and/or proparacaine. PDE-5 inhibitor therapy. (iii) Surgical treatment including dorsal penile nerve block, etc. Note: concomitant diseases such as erectile dysfunction, urethritis, and chronic prostatitis should be treated separately.