Chest tightness and inability to take a breath do not matter for those with milder symptoms; patients with more severe symptoms may have a tendency to faint. Always feel the stone pressed in the chest, breathing is more difficult. The causes of chest tightness and inability to get up air are: a. Mood and space. Sometimes impatient mood and airless space are the main reasons for chest tightness and inability to get up air. This is also the reason why many office workers have chest congestion. Second, disease. Long-term chest tightness, the phenomenon of not being able to breathe, may be caused by disease. Diseases that cause chest congestion and breathlessness include abnormalities in the respiratory tract, lungs, heart and other parts of the body, which can easily cause chest congestion and breathlessness.