The difference between hand eczema and tinea versicolor mainly includes different etiologic causes, different clinical manifestations, different treatment modalities, and different prognoses. 1. Different etiology: the cause of hand eczema is complicated, and it is considered to be related to family genetics, special occupations, contact with allergens, humid living environment, diet and other factors. Ringworm, on the other hand, is a fungal skin disease, the causative organisms include Trichophyton rubrum, Trichophyton mustelii and so on. 2. Clinical manifestations are different: eczema caused by skin damage, mainly including the palm of the hand, the back of the hand, finger areas appear dry, red, edema-like hypertrophy, small blisters, scales, may be accompanied by obvious itching. And blistering tinea versicolor, often manifested as between the fingers, the palm of the hand may appear deep in the blisters. Keratosis pilaris, often manifested as dry and thickened skin, rough and flaky, deepening texture. Impregnated vesicular tinea versicolor, there may be vesicles, oozing. 3. Different treatments: hand eczema is related to allergens, contacts, chemicals and other factors, it is recommended to find and remove the triggers. Treatment drugs include loratadine, cetirizine hydrochloride, retinoic acid, mometasone furoate, prednisone and so on. Ringworm treatment drugs are mainly antifungal, including compound bifonazole solution, terbinafine cream and so on. 4. Prognosis is different: patients with hand eczema may develop again if they come into contact with allergens and blood circulation disorders again. Ringworm, antifungal treatment is more effective, usually pay attention to avoid the cause of the disease, generally will not get sick again. To summarize, the difference between hand eczema and ringworm is more, it is recommended to go to the hospital dermatology department, under the guidance of the doctor with medication.