Mole spotting is generally more effective with laser than potion. Laser mole spotting can control the depth and range of operation, safe operation, not easy to hurt the surrounding normal skin. The photoelectric operation used for mole spotting includes high-frequency electric knife, carbon dioxide laser, etc. Before the operation, usually topical epineural medication is used, and there may be slight burning pain during the process. There will be scabbing and scab removal during the healing process, and the wound can be recovered in 7~10 days in general. Medicine mole spotting is generally choose strong acidic or alkaline chemicals in the local corrosion, this method is generally not easy to control the scope and depth of mole spotting, improper treatment is very easy to make the surrounding normal tissue involved and cause chemical burns. At present, regular medical institutions have basically abandoned this treatment program. Mole spotting should go to regular hospitals, operated by professional physicians, and pay attention to scientific care after treatment to avoid adverse consequences.