The best treatment for acute myocardial infarction is to open the vessel as early as possible when it is acutely occluded, and the way to open it is thrombolysis or direct stenting. The relief of chest pain and decrease of cardiac enzymes after infarction does not mean that the vessel has been opened. If the vessel is still occluded or has severe stenosis, a stent should still be implanted. One minute earlier opening after acute myocardial infarction can save one more patient with acute myocardial infarction. The blood vessel can be opened in the shortest possible time. As the saying goes, “time is myocardium, time is life”. It is ideal to do coronary angiography and stent implantation within 4-6 hours after the onset of acute myocardial infarction if the patient is in a position to do so, but if not, at least thrombolysis should be done in situ. If the onset is more than 6 hours and the window time for thrombolysis is missed, but still within 12 hours, coronary angiography and stent implantation should also be done as soon as possible.