The duration of anticoagulation therapy for patients with pulmonary embolism varies from person to person. For pulmonary embolism caused by surgery, trauma and other factors, treatment is required for 3-6 months; for patients with unknown source of emboli, treatment is required for more than 6 months; for patients with recurrence, or combined pulmonary heart disease and long-term risk factors, such as cancer, easy embolism or implanted inferior vena cava filter, the course of treatment is at least 12 months, or even required lifelong anticoagulation therapy. The decision of when to stop anticoagulation therapy should be made by the physician based on the patient’s specific situation and the results of the examination. Finally, it is important to remind medical professionals that health education is particularly important for patients taking warfarin anticoagulation, whose compliance directly affects their prognosis.