There are many reasons why patients wake up at night with numb hands: 1, may be caused by pressure on one side of the limb, resulting in poor local blood circulation and hand numbness, when the pressure is lifted, hand numbness can be relieved. 2, may be related to the sleep posture or pillow is not appropriate, if the patient has cervical spondylosis, these causative conditions can easily lead to the patient’s nerve roots are compressed, the symptoms of hand numbness. 3, night Waking hand numbness is considered a cerebrovascular disease, cerebral infarction is prone to occur when the patient sleeps, the patient will show numbness in the hands. Located on the opposite side of the lesion, causing the patient to have hand numbness, problems in the thalamic area are likely to occur, which may be thalamic infarction or transient ischemic attack in the thalamus.