The photodynamic therapy program for warts mainly consists of two parts: debugging the photosensitizer and irradiation dose and selecting the sensitive light source. 1. Debugging photosensitizer and irradiation dose. First of all, the modulation of photosensitizer, the preparation of ALA solution concentration of 10% ~ 20%, the state of the gel, the dose of ALA concentration energy density of 100 ~ 150J per square centimeter, the power density of 60 ~ 100mW per square centimeter, the time of dressing for 3h, the treatment of the first cavity microscopy to determine the scope of the lesion, the scope of the dressing, including the surface of the lesion and its periphery within the area of 1cm. 2. Choose a sensitive light source. Clinically, the urethral acromegaly choose 630nm or so semiconductor laser and column diffusion fiber; cervical acromegaly use 630nm or so semiconductor laser and microlens fiber, can also be used with the uterine cavity cervical cap of the optical fiber. Anal canal condyloma acuminatum is treated with an LED light source specially designed for use in the cavity or with a semiconductor laser around 630 nm and a main diffusion fiber. Patients follow-up 1 week after treatment, warts have not completely disappeared can repeat the treatment, no special circumstances 1 week treatment once; if after 3 treatments, the lesions subside <50%, it is recommended to change or combined with other therapies; warts subside under the naked eye, can be consolidated 1 to 2 times of treatment; warts are completely cleared, the end of the course of treatment, follow up every month, lasted up to 6 months. It is recommended that the patient according to their own symptoms timely to the regular hospital treatment, so as not to delay the condition caused by serious consequences.