Newborn babies have more eye problems during the neonatal period. The common problems are mostly tears and discharge, mostly unilateral and can be bilateral. The essence is that a place called ‘nasolacrimal duct’ is not open, and we know that when sad and tearful will nasal snot and tears. This is the reason why tears flow into the nasal cavity. In normal circumstances in order to ensure the lubrication of the eye also to have tears secretion, if the nasolacrimal duct is blocked, there will be tears, or even secretions. This condition is also known as congenital lacrimal duct obstruction and is a common eye condition that occurs in newborns. The incidence is reported to be about 6% in newborns, with no gender differences in onset, mostly unilateral, and 1/3 bilateral. The vast majority of cases develop 5 to 18 days after birth, and a few can have a family history. The majority of cases are caused by the lower exit of the nasolacrimal duct in the nasal cavity being closed by membranous tissue or by epithelial cell debris blocking the duct. In a few cases, it may be caused by bony stenosis or nasal malformation. It is usually unilateral, but there are also bilateral cases. It may open naturally usually around 1 month after birth, otherwise it may lead to dacryocystitis, secondary lacrimal adhesions, conjunctivitis, and even eyelid and corneal infections. How to treat congenital lacrimal duct obstruction? Overflow of tears and increased secretion are the main manifestations of congenital lacrimal duct obstruction. Dye drainage test, lacrimal duct flushing and lacrimal ductography are the main methods to diagnose congenital lacrimal duct obstruction. The course of some children with congenital lacrimal duct obstruction is self-limiting. For children under 3 months of age, lacrimal duct massage combined with antibiotic eye drops can be given. If lacrimal sac massage is not effective, lacrimal duct irrigation is an option. If the lacrimal duct is still not open after more than 3 lacrimal duct irrigations, lacrimal duct exploration can be considered. For children who have failed to pass the lacrimal duct twice and for older children, surgical treatment such as lacrimal duct placement may be considered. Conservative treatment can be done with topical tobramycin drops or pressure massage, directed toward the nasal cavity, 2-3 times a day. This method is most effective in children 1 to 3 months of age and less effective in children older than 6 months of age.