The drugs used in the treatment of SLE broadly include non-steroidal anti-inflammatory drugs (NSAIDs), anti-malarial drugs, glucocorticoids and immunosuppressants.
1. Non-steroidal anti-inflammatory drugs: Non-steroidal anti-inflammatory drugs have anti-inflammatory and analgesic effects, which can relieve joint and muscle pain in patients with mild SLE, and common drugs include ibuprofen and indomethacin. Attention should be paid to the side effects of peptic ulcer, bleeding, kidney and liver function.
2. Anti-malarial drugs: can control systemic lupus erythematosus rash, reduce photosensitivity, but also conducive to patients to stabilize the condition and reduce the dosage of glucocorticoids, including chloroquine, hydroxychloroquine and so on.
3. Glucocorticoid: glucocorticoid can be applied to all types of SLE patients, and individualized glucocorticoid treatment can significantly inhibit the inflammatory response. In the acute stage, it can rapidly control the disease, prevent or delay the damage of internal organs, and consolidate the therapeutic effect after the disease is relieved to prevent the disease from rebounding. Commonly, such as prednisone.
4. Immunosuppressant: It can reduce the accumulated use of glucocorticosteroids and have the effect of preventing disease recurrence. Common immunosuppressants include Merti-macrolide, Tacrolimus, Methotrexate, etc. It is necessary to pay attention to monitoring blood routine, liver and kidney function.
SLE patients are advised to go to the rheumatology and immunology department of regular hospitals, and the above drugs should be taken according to the doctor’s prescription, and should not be blindly self-medication to avoid adverse reactions.