Calcitoninogen in healthy people is extremely low, generally less than 0.05 ng/ml. high calcitoninogen is usually caused by bacterial infections, fungal infections and other causes. clinical monitoring of elevated calcitoninogen can determine the type of infection occurring in the patient’s body and the severity of the infection. Common causes 1, bacterial infection: Calcitoninogen is a specific serum marker, the specificity and sensitivity of detecting bacterial infection is above 90%, and it is linearly correlated with the severity of bacterial infection, that is, the higher the calcitoninogen value indicates the more serious infection; 2, fungal infection: for example, superficial fungal disease, skin fungal disease, systemic fungal disease, etc., can also lead to high calcitoninogen, which can be combined with fungal microscopy 3. Parasitic infections: common diseases such as malaria and amoebic dysentery can lead to high calcitoninogen, which can be diagnosed by stool examination and blood smear examination. 4. In addition, calcitoninogen may increase physiologically in newborns within 2 days after birth. If the calcitonin level decreases after treatment, the patient’s condition is gradually improving and the infection is effectively controlled. During the treatment period, patients need to maintain a positive and optimistic attitude to face the disease in order to promote the recovery of the organism.