Fat grains may be the manifestation of cornu rashes, sweat duct tumors and other skin diseases, there is no such thing as the fastest elimination method, usually choose medication, surgical treatment, physical therapy and other methods to eliminate. 1. Medication: For the fat granules caused by cornu rashes, topical retinoic acid preparations should be used under the guidance of medical professionals. 2. Surgical treatment: Surgical excision can be taken for larger fat grains caused by sweat duct tumor. 3. Physical therapy: laser ablation is the common treatment for fat granules. Electric drying method, chemical peeling, grinding, etc. can also be used for the treatment of lipogranuloma. Most of the fat grains do not need treatment. If there is a need for treatment, it is recommended that the patient should go to the hospital in time and receive standardized treatment under the guidance of the doctor.