Drug allergy How long does it take to get better after taking loratadine depends on the severity of the condition, if the symptoms are mild, it can be improved in a short period of time after stopping the drug and symptomatic treatment; if the symptoms are more severe, it depends on the condition and the response to the treatment. If the symptoms of drug allergy are mild, such as bright red papules, purplish-red patches, asymmetric round edematous red patches, obvious itching, etc., usually after stopping the allergy-causing drugs, drink more water to excrete the allergy-causing drugs, take loratadine, and oral glucocorticosteroids at the same time, if necessary, a short period of time can be good. Drug allergy if the symptoms are more serious, in addition to the above skin symptoms, can also involve the eyes, mouth, respiratory tract and gastrointestinal mucosa, at the same time may be accompanied by bronchial asthma, abdominal pain, diarrhea, high fever, toxic hepatitis, thrombocytopenia and other systemic manifestations, need to go to the hospital hospitalization, the specific time to get better depending on the condition. Loratadine may cause weakness, drowsiness, headache, nausea and skin rash and other adverse reactions, it is recommended to use under the guidance of a doctor, if the symptoms are more serious, it is recommended to go to the hospital in a timely manner.