Treatment of Mycoplasma solium infection is now mostly advocated to be treated when there are symptoms, regardless of whether the infection is in men or women, and can be left untreated if there are no symptoms. There are many drugs available for the treatment of Mycoplasma solani infection, such as doxycycline hydrochloride, clarithromycin, azithromycin, memantine, and cross-transomycin, and many other drugs. The patient is given a culture of mycoplasma plus a drug sensitivity test before treatment of mycoplasma infection, from the drug sensitivity test to select a sensitive antibiotic, and combined with the patient’s physical condition and other circumstances for drug treatment, men with drug treatment can generally be cured, some women are not cured, but it does not matter, mycoplasma has very little impact on people.