Pulmonary hypertension is a chronic disease with a high mortality rate. Due to the lack of oxygen, the lips of patients are often blue, which makes “blue lips” synonymous with this particular group of patients. So what kind of disease is pulmonary hypertension? What are the risks? What do patients with pulmonary hypertension need to pay attention to in treatment? And what can we do for the “blue lips”? What is pulmonary hypertension? When it comes to hypertension, I think we all have a certain concept, that is, systolic blood pressure ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg, the blood pressure referred to here is the “body circulation – body artery” blood pressure reflected by measuring the blood pressure of the upper limb artery (brachial artery), but in addition to the body circulation, there is another important set of In addition to the body circulation, there is another important circulation in the body: the pulmonary circulation, through which the body provides oxygen to all systems of the body. The pulmonary artery is located in the thoracic cavity, and we cannot measure it by an easy method like measuring blood pressure, but need to measure it by inserting a catheter (right heart catheter) from the peripheral vein, through the right heart and then to the pulmonary artery. Therefore, its diagnostic criteria are: the mean pressure of the pulmonary artery ≥ 25 mmHg detected by the right heart catheter at sea level and at rest. The right heart catheterization is an invasive operation and relatively complicated, and cardiac ultrasound can provide us initial clues for the diagnosis of pulmonary hypertension. With cardiac ultrasound we can roughly estimate the systolic pulmonary artery pressure. When the systolic pulmonary artery pressure is between 36 and 50 mmHg, a right heart catheterization needs to be considered to further clarify the presence of pulmonary hypertension and to help define the type of pulmonary hypertension. What are the risks of pulmonary hypertension? In the disease of pulmonary hypertension, the pressure in the pulmonary circulation increases, which in turn causes an increased burden on the right heart. Long-term high workload on the right heart can lead to an enlarged right heart, which in turn can compress the left heart, causing a decline in left heart function as well, and eventually left and right heart failure. Both early right heart insufficiency and eventual total heart insufficiency can cause insufficient oxygen supply to internal organs, resulting in respiratory distress, especially after activity, decreased exercise endurance and impaired quality of life; at the same time, it may be combined with impaired body circulation, manifested as lower limb edema, pleural effusion, abdominal effusion, abnormal liver function, and even shock and coma. What do patients with pulmonary hypertension need to pay attention to in their lives? Patients with pulmonary hypertension need to pay attention in the treatment process: 1. oxygen: it helps to improve exercise tolerance and cardiopulmonary function, and it is recommended to carry out oxygen therapy under the guidance of doctors; 2. medication according to medical prescription: treatment of pulmonary hypertension may involve diuretic, vasodilator, anticoagulation and other aspects, in the long-term treatment of patients, good interaction between doctors and patients is very crucial, patients must strictly follow medical prescriptions for medication, and doctors should 3, close monitoring of adverse reactions: a variety of drugs have therapeutic effects may also have adverse reactions, patients should pay attention to observe and promptly reflect to the doctor, for example, diuretics may lead to loss of body salt (electrolytes), dehydration and weakness, lethargy, palpitations, need to regularly recheck the body electrolytes, anticoagulant drugs used to pay attention to whether anticoagulation to achieve the therapeutic goals The use of vasodilators may lead to hypotension or dizziness, headache, nausea and vomiting due to intracranial vasodilatation, etc. Once various adverse reactions occur, prompt medical attention should be sought. In addition, patients need to consult their doctors about various factors that may aggravate the burden of cardiac function, such as pregnancy, prolonged outdoor exercise and highland travel. In conclusion, patients with pulmonary arterial hypertension should consult with their doctors if any new symptoms appear, or if the existing symptoms worsen, or if new aggravating factors are expected to appear, during the treatment and observation process. What can we do for the “blue lips”? Pulmonary hypertension – a special group of people with “blue lips” – is a special group that needs attention. In China, most of the drugs used for the treatment of pulmonary hypertension are not covered by medical insurance, such as sildenafil, tadalafil, bosentan, and aniracetam, etc. Therefore, once diagnosed with “pulmonary hypertension”, it means a heavy medical and financial burden. We hope that more drugs for the treatment of pulmonary hypertension will be covered by medical insurance, so as to provide more choices for the “blue lips”. Pulmonary hypertension was previously thought to be a rare disease, but in reality it is not, but more common. Here, we call for more medical personnel, including those from respiratory and critical care medicine, cardiology, cardiac surgery, pediatrics, gynecology and other related disciplines, to pay attention to this group, to improve the diagnosis and treatment of pulmonary hypertension in China, and to provide more practical medical protection for the “blue lips”.