Clomipramine hydrochloride tablets in the treatment of premature ejaculation during the larger side effects, the current clinical rarely used, can be replaced by dapoxetine hydrochloride and other drugs, specific instructions. Clomipramine hydrochloride tablets belong to the tricyclic antidepressants, can play the antidepressant, anxiolytic, sedative and anticholinergic effects, is suitable for the treatment of various depressive states, but also commonly used in obsessive-compulsive neurosis, phobic neurosis, and can also be used for the treatment of premature ejaculation, but due to the large number of side effects, it has been rarely used. For the treatment of premature ejaculation, dapoxetine hydrochloride can be used, among others. Clomipramine hydrochloride tablets should be contraindicated in people who are allergic to tricyclic drugs, children under 6 years old, people who have a recent history of myocardial infarction seizure, people with severe heart disease, epilepsy, glaucoma, and urinary retention conditions. Anticholinergic reactions such as excessive sweating, dry mouth, blurred vision, dysuria, constipation, etc., as well as adverse reactions such as drowsiness, tremor, vertigo, postural hypotension, etc., may occur in the early stage of treatment. Specific medication should be administered under the guidance of a specialist and should not be used without authorization.