Yellow sputum and yellow nasal mucus are mostly caused by infections, and can be treated with oral roxithromycin, cefixime anti-infection, ambroxol, carboxymetholestane to resolve phlegm, but also oral ambroxol oral solution to resolve phlegm and local nasal irrigation and other symptomatic treatments. 1. Anti-infection treatment: yellow nasal discharge, yellow sputum, commonly caused by rhinitis, sinusitis, pharyngitis, upper respiratory tract infection, acute tracheobronchitis, pneumonia and other infections, oral antibacterial drugs such as roxithromycin capsules, cefixime, amoxicillin, etc., greater than 18 years of age, but also oral levofloxacin tablets and other quinolone antibiotics. 2. Symptomatic treatment: the appearance of sputum thick can be oral aminoglutethimide, carboxymethylstilbestrol, acetylcysteine effervescent tablets or nebulized acetylcysteine solution to resolve sputum, sinusitis can be used to rinse the nasal cavity with sea saline, but also selective sinus puncture drainage. If yellow snot, yellow snot, self medication is not effective, it is recommended to consult a doctor in time, improve the blood routine, chest CT, sinus CT and other auxiliary tests to further clarify the diagnosis of the cause of the treatment, and under the guidance of the doctor to apply medication and related therapies.