I had a question from a patient’s family. His father underwent aneurysm embolization after bleeding from a ruptured aneurysm, and the patient recovered afterwards, but then he underwent lumbar pool drainage. The doctor said that the brain crest fluid culture was drug-resistant A. baumannii and gave them a critical illness, saying that the mortality rate was very high and there was basically no possibility of cure or that he would be a vegetable even after cure. In order to better treat patients, doctors may perform some invasive operations, including craniotomy, ventricular drainage, lumbar pool drainage, ventriculoperitoneal shunt, etc. These operations may open up the brain tissue or crestal medulla, which is originally protected by the scalp, skull and meninges, to the outside world, resulting in opportunities for pathogenic bacteria to take advantage of. The common pathogenic bacteria of intracranial infections are mostly gram-positive cocci, but in recent years, with the application of a variety of high-level antibiotics and the “clinical abuse” of intracranial infections caused by excessive fear, so that the intracranial infections, which are still quite treatable, have developed into drug-resistant bacteria that are difficult to cure and even incurable, and some people will be infected Some “super drug-resistant bacteria” or fully drug-resistant bacteria, the common clinical antibiotics are ineffective, which is a very terrible clinical thing, equivalent to farmers planted by the crops of worms persecuted. But all the pesticides we can use are ineffective against it, and the end result is that the crops are spoiled by the pests and the farmers do not harvest. So in his father’s case, the doctor told him that it is very serious, even becoming a vegetable or dying, is possible. Is there a cure now? Can we only wait for death? In a case like his father’s, we can only say that it is very difficult, and there may not be a good way for general neurosurgery, and some hospitals may directly advise the family to give up treatment because this disease may cost a lot and eventually still cannot be cured. However, for septic resistant bacterial infections like his father’s, there is a whole set of “brain crest specialist techniques” that can solve the problem very well in most cases. Can I give him a detailed explanation of the disease and its treatment? Early intracranial infections usually present with fever, headache, vomiting, impaired consciousness, and cervical tonicity. Bacterial culture of brain crest fluid can be positive, and there are many changes in brain crest fluid properties and laboratory tests, and the infection of Acinetobacter baumannii, Klebsiella pneumoniae and Pseudomonas aeruginosa (green pus) is mostly manifested as purulent brain crest fluid. However, most of the infections can be cured after a series of “brain crest fluid specialist treatment” in the early stage. Therefore, the brain crest fluid department suggests that the appearance of intracranial infection must be treated early with regular and correct brain crest fluid treatment, and delayed treatment may lead to a disease that is difficult or even impossible to cure. In his father’s case, drug-resistant Acinetobacter baumannii has been detected, is there any hope for a cure? I replied that in his father’s case, the infection is not advanced, but only at the early stage of the disease, and the chance of cure is still very high. Normal brain tissue is protected by the meninges, the skull and the scalp to have a low chance of infection, but once these barriers are broken, pathogenic bacteria can easily invade the skull and lead to intracranial infections. Intracranial infections are a common site for neurosurgical infections, accounting for 89.80% of all infections and a mortality rate of 21%, with some “super-resistant bacteria” considered to have a 100% mortality rate. The common pathogens of intracranial infections are mostly Gram-positive cocci with mild symptoms and relatively simple treatment; however, the incidence of Gram-negative bacilli has increased significantly in recent years, accounting for more than 30% of intracranial infections, which may be related to the increased clinical emphasis on prevention of Gram-positive cocci infections in recent years. ～The rate of death is as high as 27% to 70%. As shown in the first picture of the article, A. baumannii has become a superbug, and once it invades the cranium, no amount of antibiotics will help it, so traditional treatment methods are largely ineffective, and even delay the treatment time. At this time, it is especially important to choose an effective and correct effective method in time. After years of clinical practice and research, the brain crest fluid department has summed up a set of “brain crest fluid neurosurgery specialist technology”, which has successfully cured thousands of acute and critical neurosurgery patients who were on the verge of death or disability after treatment failed in many top hospitals in China, and won good reputation from patients.