Panic and weakness can be caused by many different reasons, such as various heart diseases, anemia, low blood sugar, low blood potassium, exertion, irregular work and rest, and so on. 1. Heart disease: In case of cardiac insufficiency, the ejection function of the heart decreases, leading to tissue ischemia and symptoms of panic attacks. Atrial fibrillation with fast ventricular rhythm can also cause panic disorder. 2. Anemia: Anemia patients have symptoms of panic attacks due to decreased oxygen transport capacity of the blood, resulting in ischemia of the tissues. 3. Hypoglycemia: Low blood glucose will induce excessive secretion of adrenaline, causing sympathetic excitation and inducing panic attacks. Blood sugar should be supplemented under the guidance of doctor. 4. Hypokalemia: As potassium is an important ion in muscle activity, severe hypokalemia induces various cardiac arrhythmias, leading to panic, and at the same time, limb weakness will also occur. 5. Exhaustion, irregular work and rest: it is easy to have mental stress and so on leading to panic and weakness, should adjust the work and rest in time. When there is panic and weakness, you should go to the regular hospital in time, and under the guidance of the doctor to treat.