The common cause of headache with bitterness and nausea is neurovascular headache, which can be triggered by a variety of factors, such as the patient’s recent excessive mental stress or work pressure, as well as reduced sleep, can lead to neurovascular headache. In Chinese medicine, the symptoms of headache, bitter mouth and nausea are considered to be caused by inflammation of liver fire, which causes blood to rush to the head, resulting in headache, bitter mouth and nausea. Patients should not eat spicy and irritating food during the headache because spicy and irritating food can aggravate the symptoms of fire and cause the headache to worsen.