1.Uterus enlargement more than the size of the uterus in two and a half months of pregnancy or a single myoma diameter greater than or equal to 5 mm 2.Myoma causes excessive menstruation or irregular uterine bleeding leading to anemia 3.Myoma fills the pelvic cavity and compresses adjacent organs, such as the bladder and rectum, causing urination and defecation difficulties 4.Myoma growth site is special, such as submucosa, broad ligament, cervical myoma, etc. 5.Myoma growth is rapid, soft, painful or malignant 6, myoma has twisted or combined with infection 7, myoma combined with infertility 8, after menopause, myoma does not shrink but increase in size Clinically, according to the patient’s age, fertility requirements, the size, location, number of myoma and other specific considerations, choose the most appropriate surgical approach.