Can weight loss cure infertility? This may sound a bit mysterious. But you don’t have to say that some patients who are severely overweight may indeed benefit from a successful pregnancy if they manage their weight in a correct and scientific way. Two months ago, we met a female patient, 28 years old, 165cm tall but weighing 80kg, who was diagnosed with polycystic ovary syndrome after her menstrual disorders and infertility. It turns out that with the advancement of medicine, the understanding of polycystic ovary syndrome has gradually improved. It has been found that it can not only cause infertility, but is also associated with a series of metabolic abnormalities, behind which there is a particularly close relationship with insulin resistance. Between 30% and 70% of these patients have hyperinsulinemia, suggesting insulin resistance, and this is closely related to excess visceral fat. If one can lose weight appropriately and reduce the proportion of body fat, especially visceral fat, one can improve insulin resistance, increase insulin sensitivity and correct metabolic disorders, which also plays an important role in the treatment of patients with polycystic ovary syndrome. From the available studies, scientific weight loss under the guidance of a physician has become one of the new treatments for patients with polycystic ovary syndrome. With a weight loss of just 5-10%, the proportion of abdominal fat can be significantly reduced, thus improving the patient’s insulin resistance and helping to restore ovulation. Of course, it must be emphasized that this weight loss must be scientific, preferably under the guidance of a professional physician, using nutritional interventions, proper diet and appropriate exercise to get the body fat percentage down. If dieting and medication are abused to reduce weight, not only may it not be effective in reducing the body fat percentage, but it will also bring new problems and will not be beneficial in managing weight and helping pregnancy. And women of normal weight should not lose weight at will, too thin will also increase the difficulty of conception.