First, semen abnormalities, such as no sperm, sperm count reduction, reduced mobility, morphological abnormalities. Factors affecting sperm production: 1, congenital developmental abnormalities such as: bilateral cryptorchidism; congenital testicular hypoplasia 2, systemic diseases, chronic wasting disease, such as: long-term malnutrition, chronic poisoning, mental overstress, excessive frequency of sex to reduce the amount of sperm. 3, local factors, such as mumps complicating orchitis, testicular tuberculosis. 3, local factors such as mumps complication of orchitis, testicular tuberculosis, etc. Second, impede sperm transportation epididymal and vas deferens tuberculosis can make the vas deferens blocked, hindering the sperm to pass; impotence and premature ejaculation often can not make the sperm to enter the vagina. Immunity factors Sperm and seminal plasma can produce antibodies against their own sperm in the body and cause male infertility, and the ejaculated sperm can’t pass through the cervical mucus because of their own agglutination. Endocrine disorders such as testicular insufficiency, primary or secondary hypogonadotropic hypogonadism and hypothyroidism can also cause infertility. Fifth, other diseases In addition to the above causes, some systemic diseases, severe malnutrition, frequent exposure to radiation, high-temperature operations, toxic effects of drugs, long-term use of crude cottonseed oil and the presence of sperm immune antibodies, etc., will cause infertility.