First, marriage problem Hepatitis B virus is mainly transmitted through blood, not through the respiratory tract or normal digestive tract to infect others, general daily contact will not cause transmission. Hepatitis B virus carriers can engage in normal work, study and social activities, except for blood donation; it does not affect education, employment, going abroad, marriage, childbirth and so on. In other words, there is no restriction for hepatitis B virus carriers to get married. Because hepatitis B virus can be transmitted through blood and sexual contact, if the spouse’s hepatitis B index is negative, they can get married after three months of hepatitis B vaccination. As long as the body produces protective antibodies (i.e. positive surface antibodies), they will not be infected. Hepatitis B patients should not get married during the active period of hepatitis. Acute hepatitis has a shorter course and can be married after six months of cure. Patients with chronic hepatitis should get married after one year of stable condition and normal liver function after treatment. Second, the problem of fertility female hepatitis B virus carriers can be completely pregnant, childbirth. However, women who are in the active stage of acute and chronic hepatitis and cirrhosis with abnormal liver function should not be pregnant for the time being. After the liver function is normal, under the guidance of doctors, choose the right time to conceive. Regular review after pregnancy. For male hepatitis B patients, if the liver function is normal, it does not affect fertility. For newborns of HBsAg-positive mothers, hepatitis B immunoglobulin (HBIG) should be injected within 12 hours after birth, the dose should be ≥100 IU, and at the same time, 10 μg of hepatitis B vaccine should be inoculated in different parts of the body, and the whole process of three times of inoculation should be completed according to the program of 0, 1 and 6 (i.e., one injection at the time of birth, one month, and one injection in the sixth month). Alternatively, a single injection of HBIG can be given within 12 hours of birth, followed by a second injection of HBIG one month later, along with the first 10 μg of hepatitis B vaccine, and the second and third 10 μg of hepatitis B vaccine at intervals of one and six months, respectively.Newborns can be breastfed by their HBsAg-positive mothers after they have received the HBIG and hepatitis B vaccine within 12 hours of birth. The risk of mother-to-child transmission is mainly related to the high or low HBV DNA load of the pregnant woman. If the mother’s serum HBV DNA level is <107 IU/ml (≈5 × 107copies/ml), the success rate of immunoprophylaxis for the newborn is almost 100%; if the mother's serum HBV DNA level is >107 IU/ml, the success rate is only 68%, and other measures need to be added.