Adenomyosis combined with adenomyoma, which irritates and causes anal cramps can be treated with oral non-hormonal as well as hormonal medications. Because adenomyosis combined with adenomyoma, caused by the anus falling, can be treated by oral non-hormonal drugs as well as hormonal drugs, then the symptoms will gradually ease. 1. Non-hormonal drugs: commonly used can be non-steroidal anti-inflammatory drugs, such as indomethacin, aspirin, acetaminophen, etc., usually with anal pain. 2. Hormonal drugs: commonly compounded short-acting oral contraceptives, such as ethinyl estradiol cyproterone tablets, drospirenone ethinyl estradiol, long-term cyclic application, can inhibit ovarian function, delay the progress of adenomyosis. The specific choice of which oral drug is effective depends on whether the patient with adenomyosis is treating dysmenorrhea, heavy menstruation, or to slow down the progress of the disease.