Toothache and trigeminal nerve pain usually belong to two diseases. Toothache and trigeminal nerve pain may be seen in two cases, i.e., dental lesions invade the trigeminal nerve and cause pain, or pain occurs in the trigeminal nerve and the patient mistakes it for toothache. Patients are advised to visit the stomatology department of the hospital to have the specific lesion clarified by the doctor and take appropriate treatment, do not pull out the teeth at will: i. Primary trigeminal nerve pain: drugs such as carbamazepine, phenytoin sodium and methylcobalamin can be applied for treatment, and patients for whom drug treatment is ineffective can be treated with radiofrequency thermal coagulation, or surgical treatment, such as trigeminal nerve closure. Second, secondary trigeminal nerve pain: mostly seen in dental lesions such as pulpitis, gingivitis, and cranio-cerebral lesions such as brain tumor, arteriosclerosis, arterial ectasia, meningitis, brain stem infarction, etc., lesions invading the trigeminal nerve can lead to pain. 1, dental lesions: gingivitis requires removal of plaque and tartar around the teeth by scaling, and local rinsing with hydrogen peroxide solution, chlorhexidine containing rinse, etc., to help eliminate inflammation This usually results in the elimination of painful symptoms. If the pulp of the tooth is not completely necrotic, it can be treated by capping the pulp, pulpotomy, etc. to try to preserve the pulp, if the pulp is completely necrotic or caused by periapical infection, root canal treatment is needed to remove the necrotic pulp and then root canal filling; 2, cranio-cerebral lesions: at this time need to actively treat the original disease, drug, surgical treatment, etc., for the existence of deterioration of the patient also need to carry out radiotherapy, targeted The specific treatment should be carried out under the guidance of doctors according to the condition; 3, other: diseases such as auditory nerve tumor may also cause trigeminal nerve pain, which may be mistaken for toothache, and need to be treated for the disease, which can improve the symptoms of trigeminal nerve pain.