Is fluoroquinolone induced neuropathy reversible?

  According to the State Food and Drug Administration (SFDA) issued a circular on the 21st, alerting to the serious adverse reactions of fluoroquinolone drugs.  Experts say that peripheral neuropathy is a known adverse effect of fluoroquinolone drugs, but recent adverse reaction monitoring data at home and abroad suggest that peripheral neuropathy caused by fluoroquinolone drugs may be irreversible. Peripheral neuropathy occurs soon after treatment with fluoroquinolone drugs, usually within a few days, and in some patients, symptoms can persist for more than a year despite discontinuation of fluoroquinolones. If a patient develops symptoms of peripheral neuropathy such as pain, burning, tingling, numbness or other sensory changes such as light touch, pain, temperature sensation, position sensation and vibration sensation, the fluoroquinolone should be discontinued and replaced with another non-fluoroquinolone antibacterial drug. Unless the benefits of continued treatment with fluoroquinolones outweigh the risks.