The common pathogenic bacteria of fungal infection of hands and feet include Trichophyton rubrum, Trichophyton mustelii, flocculent epidermidis and so on, and the common manifestations include blisters, peeling skin and erosion. 1. Rash site: it can occur in unilateral hand and foot, or left and right side at the same time, such as hand and foot dorsum or between hand and toe or side. 2. Symptoms: Itchiness, pain, etc., some of which may be cracked or bleeding, especially after the application of detergents, which aggravates the itching. 3. Rash manifestations: there can be erosion, maceration, oozing, or even epidermal peeling between the fingers or toes, accompanied by erythema, with papules, small blisters, papules and other manifestations, and some of the blisters can form scabs and flakes after breaking, and even blisters merge with each other to form an eroded surface. When fungal infection occurs, it is recommended to consult a doctor in time, follow the doctor’s instructions for further examination, with the help of the doctor to clarify the cause, targeted treatment or therapy.