Neonatal hyperbilirubinemia needs to be treated as early as possible, and the specific measures are as follows: 1. Phototherapy, the most important method of treatment for neonatal hyperbilirubinemia, can be used to reduce bilirubin encephalopathy and prevent the occurrence of nuclear jaundice, and effective phototherapy helps to reduce the number of blood changes and can reduce the pain of the child. Treatment can be performed with facilities such as fiber-optic beam blankets or LED phototherapy lamps; 2. Further aggravation of the disease may require blood exchange therapy, which is generally used when phototherapy fails. Blood exchange therapy can effectively reduce bilirubin, exchange out the sensitized red blood cells and reduce anemia, but blood exchange may produce certain adverse reactions; 3, drug therapy, can be used to inhibit the production of bilirubin and promote the removal of bilirubin, commonly used in traditional Chinese medicine gardenia yellow granules.