1.Why do patients become deaf? A. According to the survey, the main causes of deafness are genetics, diseases, drugs, accidents, disasters, environment, pollution and other factors, which is the consensus of experts in the field of clinical otolaryngology for many years. 2.How can we determine the cause of deafness? A. The current genetic technology can diagnose deafness caused by genetic factors. 3ml of venous blood is taken from a patient for gene chip testing, and the cause of deafness caused by genetic factors can be identified. 3. What kind of diseases are related to genetic factors? A. Moderate to severe bilateral sensorineural deafness, patients with vestibular conduction duct syndrome, patients with deafness caused by the application of drugs. Patients with acquired high frequency sensorineural deafness familial deafness 4. What kind of patients are likely to be caused by genetic factors? (1) The patient fails bilateral hearing screening at birth (2) The patient has normal hearing at birth, and as he/she grows older, at the age of 3-7 years or during adolescence, the patient’s hearing decreases in waves. (3) hearing at birth is normal, but at any age, the application of aminoglycosides (gentamicin, kanamycin, streptomycin, butylamine kanamycin, macromycin, tobramycin, nontinamycin, etc.) hearing loss (4) hearing at birth is normal, but after 1 year of age, high-frequency sensorineural hearing loss. 5.Is it possible that a child of a healthy couple is deaf due to genetic factors? A. Eighty-five percent of deaf children are born to normal couples because the child has a pair of genes, half from the father and half from the mother. The parents themselves carry only half of the genes that cause deafness, but the child receives half of the genes that cause deafness from each parent, so deafness will occur. 6. Is there any other way to diagnose hereditary deafness besides gene chip technology? A. Currently, the only way to diagnose hereditary deafness is through genetic testing. 7.The patient passed the hearing screening test at birth, but now her hearing is gradually decreasing, could it be hereditary deafness? A. Yes. Because vestibular canal syndrome, some neurological deafness and drug-related deafness are normal at birth, and hearing loss occurs gradually with age, there is a high possibility that it is caused by hereditary deafness. 8.Can all hereditary deafness be detected? A. The current gene chip technology is not able to detect all genetic disorders. GJB3, for bilateral acquired high-frequency sensorineural deafness, but it basically covers about 80-90% of the above four genetic deafness defects in Chinese people. How can I avoid it if I want to have a second child? A. Gene chip testing of the deaf child and parents is required to determine if the child is genetically deaf, and if this is confirmed, then genetic counseling and intervention should be performed when the second child is conceived to prevent the birth of another deaf child. 10. A. A gene chip test is needed to diagnose whether the deafness is caused by genetic factors. How long does it take to get the results? A: Currently, the genetic deafness microarray test at Tong Ren Hospital costs RMB 1,000 per person, which is reimbursed by Beijing Health Insurance. The report will be available at the laboratory in about 5 working days. 12.What should I do when I get the gene microarray report? A. Please consult your clinician to get the relevant diagnostic instructions, and then proceed with the treatment under the guidance of your doctor. 13.How to do the gene chip test? A. Patients need to register at the Ear Clinic of Tong Ren Hospital, find an otolaryngologist, issue the gene chip test form, pay the fee at the charge office, and then go to the blood collection center to collect 3 ml of venous blood and send it to Dr. Zhao in Room 212 on the 2nd floor of the Ear Institute of Tong Ren Hospital East for registration and filing (patients need to bring their outpatient medical records).