Chest tightness after drinking is often due to increased sympathetic excitability induced by alcohol, which results in faster heart rate, increased myocardial oxygen consumption, and symptoms related to angina pectoris. Drinking alcohol can lead to vasodilation in a short period of time and a moderate decrease in blood pressure. Long-term, heavy drinking often results in increased blood pressure, progression of atherosclerotic disease, and even alcoholic heart disease. Changes in the structure and function of the heart can be reversed by alcoholic heart disease through abstinence from alcohol and systematic related treatment. Therefore, for the general population as well as patients with underlying organic heart disease, it is recommended to quit smoking and limit alcohol, eat a low-salt, low-fat diet, and exercise appropriately to maintain an optimistic and positive attitude toward life.