Dilated cardiomyopathy refers to primary cardiomyopathy, its etiology and pathogenesis is unclear, domestic and foreign research data show that: 1, and infection-related. In animal experiments, cardiophilic coxsackie B3 virus can not only cause myocarditis, but also can lead to myocardial lesions similar to dilated cardiomyopathy, and clinically it was also found that patients with acute myocarditis can be transformed into dilated cardiomyopathy, and enterovirus RNA can be detected in the myocardium of 10%-50% of patients with dilated cardiomyopathy; continuous testing of patients in the transformation from myocarditis to dilated cardiomyopathy confirmed the presence of Enterovirus RNA persistence, it is believed that the state of virus persistence is related to the control of enterovirus RNA replication finger gene mutation. 2, and immune related. It is believed that the transformation process of myocarditis to dilated cardiomyopathy may be related to the immune dysfunction of the body, especially the expression of human leukocyte antigen-II has high tissue specificity, and the ectopic expression in the heart of dilated cardiomyopathy is extensive and involved in myocardial injury. 3. Related to genetic factors. Dilated cardiomyopathy can have a familial onset, and both sex chromosomal genetic and autosomal dominant inheritance have been reported. 4, other. Associated with drugs, toxins, malnutrition, etc.