Dust mites are common allergens, which mainly cause allergic rhinitis and allergic asthma. With the modernization of social life and the changing indoor living environment, the incidence of dust mite allergic asthma is also increasing. Desensitization therapy, also known as specific immune response therapy, is a treatment method that can alter the course of allergic diseases. Mechanism of desensitization therapy After identifying the allergen of a patient with an allergic disease, the allergen is made into an allergen extract and configured into various preparations with different concentrations, and the patient is repeatedly exposed to the allergen by repeated injections or through other routes of administration in small to large doses and low to high concentrations, and maintenance treatment is carried out after the effective dose is reached, thereby improving the patient’s tolerance to the allergen. When the allergen is re-exposed, the allergy no longer occurs or is reduced. The advantages of desensitization therapy Desensitization therapy is the only allopathic treatment recognized by the WHO that can influence the pathogenesis of allergic diseases, reduce the use of controlled medication in asthma patients, reduce the emergence of new allergen sensitization, have long-term effects and prevent further development of allergic diseases, reduce the severity of asthma patients, serve as a complementary treatment to allergen avoidance and medication, and also improve the quality of life of patients with allergic diseases. Desensitization therapy with conventional medications Desensitization therapy for asthma patients is combined with asthma medications, which are divided into two main categories: long-term control medications and symptom-relieving medications. Long-term asthma control medications are medications that are used daily over a long period of time and are designed to suppress airway inflammation, maintain normal or approximately normal lung function in patients, and prevent or reduce asthma attacks. Relief medications are medications that work quickly to relieve bronchoconstriction, release smooth muscle spasm and the resulting acute symptoms of cough, wheezing, chest tightness, shortness of breath, etc., and are used as needed during an attack.