The PCR technique has high specificity and sensitivity The technique has been widely used in the medical field as well as in dermatological examinations, and it is currently considered the best method to detect HPVDNA and typing. The PCR technique for HPVDNA detection using fresh lesions, secretions or mucus specimens is not only used for clinical HPV-induced diseases and to investigate the rate of HPV infection in different populations or individuals, but also for the study of HPV pathogenesis and carcinogenesis, – A large number of studies have shown that the positive rate of HPV-DNA detection by PCR technique is HPV-DNA has a much higher positive rate than other testing techniques and is the most common tool used today for the diagnosis of HPV (type 6/11) in condyloma acuminata and HPV (type 16/18) which is associated with cervical cancer.