Dry eyes, soreness and fatigue may be caused by dry eye syndrome, blepharosphenoid gland dysfunction and refractive error, etc. Patients can follow the doctor’s instructions to use medication, physical therapy, optical correction, etc., to alleviate eye discomfort. Patients with dry eyes, soreness, fatigue, may be caused by dry eye, because the tear film is not stable, patients are prone to dry eyes, foreign body sensation and other symptoms of discomfort, patients can follow the doctor’s instructions to use sodium vitreous acid drops and other artificial tears to moisturize the surface of the eye, to alleviate the symptoms of ocular discomfort. Similar symptoms can also occur if the patient has a blockage of the blepharoplasty gland opening that leads to lipid secretion disorders. The patient can have a blepharoplasty massage to unclog the opening and the ducts to relieve the symptoms. Patients with refractive errors such as myopia and astigmatism who have not corrected their refractive errors in a timely manner are prone to visual fatigue because of blurred vision, and patients can correct their refractive errors by wearing eyeglasses to improve their discomfort. It is recommended that patients with noticeable dryness and soreness of the eyes should seek prompt medical attention to assess their condition and follow the doctor’s instructions for treatment.