Mole generally refers to melanocytic nevus, which is mainly caused by benign proliferation of melanocytes, and laser mole removal is a common clinical treatment method. Whether laser mole removal is painful or not varies from person to person. For most people, the pain during laser treatment is small and can be tolerated by patients; while for people with sensitive skin, who are less tolerant to laser pain, they may feel more painful and can take oral painkillers or choose local anesthesia before surgery if they cannot tolerate it. The local injection with anesthesia needle will also be slightly painful, which is generally tolerable, so as to reduce the stinging and burning sensation during the laser treatment. Laser mole removal is basically painless after the operation because the operation has the advantages of fast, small invasion and no bleeding, and it usually takes about 2 weeks to recover. However, it should be noted that the laser mole removal site should avoid water, pay attention to local dryness and cleanliness to avoid causing infection, redness, swelling and pain. If necessary, oral antibacterial medication and topical anti-inflammatory drops and creams should be applied to promote recovery and achieve the expected results. After scab formation, it is recommended to let it fall off naturally to avoid scratching by oneself to cause secondary trauma, which will eventually lead to pigmentation or scar formation. During the post-operative recovery period, pay attention to a light diet, do not eat spicy, greasy and stimulating foods, and try not to wash your face with cold water or use too many cosmetics during laser treatment to avoid stimulating the local skin and affecting the recovery.